Founded in 2002 by Dr. John Nichols, Piedmont Reproductive Endocrinology Group (PREG) is a private infertility clinic, and we are consistently recognized nationally for our exceptional pregnancy success rates. We now have five in-house physicians - John Nichols, John Payne, James Holman, Travis McCoy, and Edward Moore - who specialize in advanced infertility treatments including IUI, IVF, laparoscopic and hysteroscopic procedures, tubal-reversal, and hysterosalpingography (HSG), plus other complex procedures.
We take a positive, compassionate approach with all of our patients. We know the amount of strength it takes to make this commitment, and we work hand-in-hand with our patients to achieve the result that's right for everyone. Every treatment plan is tailored to the individual patient, taking into account, age, lab results, medical history, and personal preference. Our doctors carefully review each case and make recommendations based on all of the gathered information.
Headquartered in Greenville, South Carolina, our nearly 7,000 square-foot facility contains a Surgical Suite, accredited by the American Association of Ambulatory Surgical Facilities, as well as InVitro Fertilization, Andrology, and Endocrine laboratories. All of our laboratories are inspected by The College of American Pathologists, as well as the CLIA, and are equipped with state-of-the-art technology and equipment.
Affording fertility treatments is often perceived as overwhelming. However, PREG is a private clinic and offers pricing and financing options that other clinics cannot. We also have financial counselors who are experts in maximizing patients' financial resources and insurance benefits. Many insurance companies cover some, if not all, of the costs of infertility treatments and medications. Click here to learn about your personal insurance benefits.
~We have financing available through Compassionate Care, a 25% discount for the armed forces, and multi-cycle discounts.
~We are a United Health Care Center of Excellence, as well as an Aetna Fertility Center of Excellence, which enables us to work hand-in-hand with the insurance companies to negotiate the best rates.
~PREG is also a preferred provider for military patients, as our own Dr. John Payne is a military veteran himself.
Physicians & Staff
What sets our physicians apart is their ability to provide sincere, compassionate, and sympathetic care - a very non-clinical approach to very clinical procedures. As a team, our goal is to exceed your expectations every visit. We have five in-house physicians: John Nichols, John Payne, James Holman, Travis McCoy, and Edward Moore who specialize in advanced infertility treatments including IUI, IVF, laparoscopic and hysteroscopic procedures, tubal-reversal, and hysterosalpingography (HSG), plus other complex procedures. Our fertility specialists are regularly recognized amongst the Best Doctors in America and America's Top OB/GYNs. Our fertility team continues to set exceptional standards as a Center of Excellence. As a team, our goal is to exceed your expectations every visit.
Third Party Reproduction Director
Want to join our team?
Send us your resume.
CNM, MSN, Nurse Midwife
RN, MSN, FNP-BC
REI Nurse and IVF Coordinator
Lab Team Member
Chief Financial Officer
Patient Account Specialist
Awards & Accolades
Having a successful practice is extremely gratifying not just for us, but for the families we serve. We are proud to be recognized for the many ways that we help women, partners, and spouses get the family they desire.
- Highest Pregnancy Rates in South Carolina for Two Years Consecutively!
John Nichols, MD
- Listed as One of America's Top Ob/GYN's
- Listed as One of America's Top Doctors
- Listed as one of Greenville, SC Top Doctors- OB/GYN
- President of the South Carolina OB/GYN Society
John Payne, MD
- Listed as One of America's Top OB/GYN's
- Listed as One of America's Top Doctors
- Listed as One of Greenville, SC Top Doctors- OB/GYN
- President of the Greenville County Medical Society