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Successful pregnancy rates from IVF can be defined in several terms. The most
useful and meaningful is the live birth rate or “take home baby rate”. This takes into account that with any couple that
becomes pregnant (either naturally or with the use of fertility treatments) there
is a risk for miscarriages or loss of pregnancy which can range from 10% or higher
depending on factors such as age of the female and history of repeated miscarriages
in the past. Another useful definition of success would be the clinical pregnancy rate which is defined as the presence of a fetal heart beat by ultrasound usually
performed at 6 to 7 weeks of pregnancy. This quoted rate is usually higher than
the live birth rate due to the possibilities of miscarriages and pregnancy losses.
Piedmont Reproductive Endocrinology Group (PREG) is proud to be members of the
American Society of Reproductive Medicine (ASRM) and Society of Assisted Reproductive
Technology (SART). As members of SART we are required to report our IVF pregnancy
success rates annually to the Center of Disease Control (CDC) and have done so
since the inception of our IVF program in 2004. Please visit their website to
view this data; www.cdc.gov/art/. It is important to note that this published data lags by about 2 to 3 years
since live birth rates are reported and therefore programs have to wait for all
live births from their patients to be recorded for that given year.
In late 2006, PREG made changes to our IVF program that included expansion of
our embryology lab, change in laboratory directorship, changes in embryo culture
and development processes and a transition into more blastocyst (Day 5) embryo
transfers. In general, embryos can be transferred on either Day 3 after fertilization
(usually a 4-8 cell embryo) or on Day 5 (blastocyst stage) depending on the number
and development of embryos formed. Advantages of blastocyst embryo transfer include
the ability to select the higher quality and more developed embryos and transfer
of usually only two embryos in attempt to continue with high pregnancy rates but
decrease the risk of multiple pregnancies including triplets or more. Not all
patients are candidates for blastocyst transfer and consultation with your physician
is recommended.
PREG understands the dangers and risks associated with high order multiple gestations
(more than 2 fetuses), and makes every attempt to avoid these high order multiple
gestations. We recognize and follow the 2009 evidence-based guidelines for the number of
embryos to transfer in assisted reproductive technology (ART) cycles set forth
by the American Society of Reproductive Medicine (ASRM) and its affiliate, the
Society for Assisted Reproductive Technology (SART).
Since most patients want to know a program’s most recent IVF pregnancy success
rates, we are happy to report our clinical pregnancy and live birth rates for 2008 below. It is also very important to note that comparisons of individual clinic’s
IVF pregnancy success rates may not be meaningful because patient medical characteristics
and treatment approaches may vary from clinic to clinic.
We have included both fresh and frozen cycles for both non-donor and donor IVF
cycles for 2008, and have also listed our 2006 and 2007 clinical pregnancy and
live birth rates.
2008 IVF SUCCESS RATES The graph below depicts the 2008 Clinical Pregnancy Rates and 2008 Live Birth Rates by age in Fresh Non-Donor IVF Cycles.
**The clinical pregnancy rate is the percent of IVF cycles resulting in a pregnancy with fetal cardiac activity within the uterus at 7 weeks of pregnancy as visualized by ultrasound. Live Birth Rate per IVF cycle start, also known as the “take home baby rate,” is the delivery of a live born fetus. The graph below depicts our 2008 FROZEN NON-Donor Egg IVF cycles Live Birth rate by age.  The graph below depicts our 2008 Fresh Donor Egg IVF and Frozen Donor Egg Embryo Transfer cycles Live Birth Rate for all ages.
*The clinical pregnancy rate is the percent of IVF cycles per cycle start resulting in a pregnancy with fetal cardiac activity within the uterus at 7 weeks of pregnancy as visualized by ultrasound. Live Birth is the delivery of a live born fetus. **A comparison of clinic success rates may not be meaningful because patient medical characteristics and treatment approaches may vary from clinic to clinic. 2007 IVF Success RatesThe graph below depicts PREG’s 2007 clinical pregnancy rate per cycle start and live birth rate per cycle start also known as the “take home baby rate” for every patient undergoing Fresh Non-Donor IVF in the 2007 calendar year at Piedmont Reproductive Endocrinology Group.
The graph below depicts our 2007 Fresh Donor Egg IVF cycles implantation rate and clinical pregnancy rate for all ages.
**The implantation rate is the total number of pregnancies (gestational sacs) within the uterus at 6-7 weeks as visualized by ultrasound, divided by the total number of embryos transferred into the uterus. In the graph above, the implantation rate is for all of our 2007 fresh donor egg IVF cycles. Each patient received two embryos during their transfer. 2006 IVF Success RatesThe graph below depicts PREG’s 2006 clinical pregnancy rate per cycle start and live birth rate per cycle start also known as the “take home baby rate” for every patient undergoing Fresh Non-Donor IVF in the 2006 calendar year at Piedmont Reproductive Endocrinology Group.
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